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In the early 1940's dental disease was one of the most prevalent health problems in the U.S., so Procter & Gamble began researching ingredients that would reduce tooth decay. In 1950 they teamed up with Indiana University to develop and test a new toothpaste with fluoride, and in 1955 they launched the Crest brand. Since that day, Crest has been a leader in dental health innovations and they intend to continue to lead the way in the pursuit of perfect oral health so that everybody can have a healthy, beautiful smile for life.