Senokot Tablets for Women

Laxatives should not be taken within two hours of another medicine because the desired effect of the other medicine may be reduced. If rectal bleeding or failure to have a bowel movement after use occurs, discontinue therapy and consult a physician, as this may indicate a serious condition. If there has been a sudden change in your bowel movements that persists over a 2-week period, consult a physician before use. Consult a physician prior to use if you are taking thiazide diuretics, corticosteroids, licorice root or other medications or health products which may aggravate electrolyte imbalance. Consult a physician prior to use if you have a kidney disorder or are taking cardiac medications such as cardiac glycosides or antiarrhythmic medications. Long-term use of stimulant laxatives should be avoided as it may lead to impaired function of the intestine, dependence on laxatives, dehydration and electrolyte imbalance (including hypokalemia). Concomitant therapy with other drugs or herbal substances known to induce hypokalemia (e.g., diuretics, adrenocorticosteroids and licorice root) may enhance the electrolyte imbalance. Prolonged excessive use or misuse of these products may also result in the development of atonic colon.

Fertility, Pregnancy and Lactation: Consult a physician before use. There are no reports of undesirable or damaging effects during pregnancy or on the fetus associated with senna preparations when used in accordance with the recommended dosage schedule. However, as a consequence of experimental data concerning a genotoxic risk of several anthranoids (e.g. emodin and aloe-emodin), use is not recommended during pregnancy. Small amounts of active metabolites (rhein) are excreted in breast milk. A laxative effect in breast fed babies has not been reported. However, use during breast-feeding is not recommended as there is insufficient data on the excretion of metabolites in breast milk. Drug Interactions: There are no known drug interactions with sennosides.

Symptoms and treatment of overdosage: The major symptoms of overdose or abuse of any stimulant laxative, including those containing senna, are griping pain and severe diarrhea, leading to excessive water loss (dehydration) and possible electrolyte imbalance (hypokalemia). Treatment should be supported with generous amounts of fluid. Electrolytes, especially potassium, should be monitored. This is especially important in the elderly. In case of overdose: Call a Regional Poison Control Centre and/or your physician and/or your local emergency number immediately, or go to your local hospital emergency, even if you do not notice any signs or symptoms. Keep all medicines out of the reach of children.