Tylenol Cold & Sinus Extra Strength Daytime + Nighttime Caplets

Effective relief of your cold and sinus symptoms, including nasal congestion, sinus pain and pressure, fever, and headache so that you can get back to normal… whatever your normal is.

Trust the relief of Tylenol Cold & Sinus to relieve your cold and sinus symptoms. Tylenol Cold & Sinus is offered in a convenient Day/Night pack for relief around the clock. For effective relief of:
  • Nasal Congestion
  • Sinus Pain & Pressure
  • Headache & Fever
  • Runny Nose & Sneezing (Nighttime Only)

24-Hour Convenience Pack contains 10 Daytime Caplets + 10 Nighttime Caplets.

Format: caplets

Dosage: Adult Use Only (12 years and older): Take 1-2 Tylenol Cold & Sinus Daytime OR Nighttime caplets every 4-6 hours as needed. Do not exceed a combined total of any 8 Tylenol Cold & Sinus Daytime or Nighttime caplets in 24 hours.

Medicinal Ingredients:

Each Tylenol Cold & Sinus Daytime caplet contains:
  • Analgesic: acetaminophen (extra strength), 500 mg
  • Decongestant: pseudoephedrine hydrochloride, 30 mg
Each Tylenol Cold & Sinus Nighttime caplet contains:
  • Analgesic: acetaminophen (extra strength), 500 mg
  • Decongestant: pseudoephedrine hydrochloride, 30 mg
  • Antihistamine: chlorpheniramine maleate, 2 mg
Non-Medicinal Ingredients: Daytime Caplets: carnauba wax, cellulose, citric acid, corn starch, D&C yellow no. 10, FD&C blue no. 1, FD&C yellow no. 6, flavour, hypromellose, magnesium stearate, mannitol, potassium sorbate, sodium benzoate, sodium citrate, sodium starch glycolate, sucralose, triacetin. Nighttime Caplets: carnauba wax, cellulose, citric acid, corn starch, flavour, hypromellose, magnesium stearate, mannitol, potassium sorbate, sodium benzoate, sodium citrate, sodium starch glycolate, sucralose.

Caution: Read the complete label before use and follow all directions. DO NOT USE with other products containing any of these ingredients, salicylates or other cough/cold or pain/fever medications. Keep out of reach of children. This package contains enough medication to seriously harm a child. Use the smallest effective dose. Do not take more than the recommended dose. Overdose may cause nervousness, dizziness, sleeplessness or severe or possibly fatal liver damage. Consult a doctor if fever lasts more than 3 days, or symptoms last more than 5 days. If symptoms worsen, or are accompanied by a high fever (>38˚C) or the production of thick yellow/green phlegm, talk to a doctor. Do not use if allergic to any of the ingredients. Discontinue use if allergic reactions such as wheezing, rash or itching develop. Use only on the advice of a doctor. TYLENOL® Cold & Sinus Daytime: Consult a doctor before use with other medications, including natural health products, prescription drugs, nonprescription drugs or if you have chronic alcoholism, serious kidney or liver disease, high blood pressure, heart or thyroid disease, diabetes, glaucoma, an enlarged prostate or if you are elderly, pregnant, or breastfeeding. TYLENOL® Cold & Sinus Nighttime: May cause drowsiness or excitability. Avoid alcohol, driving or other activities requiring alertness. Talk to a doctor before use if you are taking tranquilizers or sedatives. Consult a doctor before use with other medications, including natural health products, prescription drugs, nonprescription drugs or if you have chronic alcoholism, serious kidney or liver disease, high blood pressure, heart or thyroid disease, diabetes, glaucoma, asthma, chronic lung disease, an enlarged prostate or if you are elderly, pregnant or breastfeeding.

Drug Interaction Precaution: Do not use with a monoamine oxidase inhibitor – (MAOI, certain drugs for depression, psychiatric or emotional conditions), or for 2 weeks after stopping the MAOI. If you are uncertain if your drug contains an MAOI, talk to a doctor before taking this product.

In Case of Overdose: contact a doctor or Poison Control Centre immediately even if you do not notice any possible signs or symptoms such as increased sweating, nausea, vomiting, stomach pain, and loss of appetite.

Warning: Do not use if carton is open or if blister unit is broken. Store at room temperature, 15-30°C (59-86°F). Protect from moisture.

Unfortunately, due to the nature of this item, we cannot accept any returns, click here for more information.
We are only able to ship this item to Canadian customers.
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Rated 4 out of 5 by from Daytime works but nighttime is another matter. Not sure why I find myself getting worse when I take the nighttime pill but I do. Daytime pills works fine and helps me get through the day. As stated previously, nighttime is an issue for me (my condition worsens significantly). As for the capsules, please consider changing the colours to reflect night and day more clearly. Night time should not be white (my opinion). Perhaps Yellow for day and blue for night I know I'm not the first to bring this up.
Date published: 2019-03-26
Rated 5 out of 5 by from Nurses Best Friend Nursing School stops for no mortal, so when I needed quick relief from congestion for my head cold I got this and it worked a miracle, 100% reccommend. I don't use anything else now when I have trouble
Date published: 2017-04-03
Rated 5 out of 5 by from Works like a dream I hate taking medicine but every time I have an unbearable cold, this is the only medicine I trust! It works incredibly fast and relieves all pain. 10/10 would recommend to anyone.
Date published: 2017-05-11
Rated 5 out of 5 by from Made me feel human again! Before trying extra strength Tylenol cold and sinus, I was so miserable that I kept asking my husband to just kill me! After getting this medication on board, I was able to get off the couch and go about my normal daily activities with minimal flu symptoms!
Date published: 2018-04-29
Rated 4 out of 5 by from Confusing colours WHY is the Tylenol Day Pill BLUE and the Night Pill Yellow. It seems counter intuitive.
Date published: 2018-03-18
Rated 4 out of 5 by from Good decongestant but awful packaging It’s a great medicine. But the packaging is terrible (peel the cover) especially when you have a fever and you need to get the medicine.
Date published: 2018-01-30
Rated 5 out of 5 by from Fantastic Product This stuff is so amazing!!! I always make sure I have some in the medicine cabinet
Date published: 2016-12-31
Rated 5 out of 5 by from It works....but...! it works. I am happy with the results whenever i need to take it. But please consider changing the colors to reflect night and day more clearly, the night time one should not be in white color
Date published: 2019-05-07
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